1 edition of Aging, genetics and the environment found in the catalog.
Aging, genetics and the environment
by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health in [Bethesda, Md.]
Written in English
Summary of the presentation by Dr. Gunther Eichhorn at the State of the Art Seminar on Aging Research given at the Gerontology Research Center, National Institute on Aging, October 1, 1976
|Series||National Institute on Aging science writer seminar series, NIH publication ; no. 79-1450, NIH publication -- no. 79-1450|
|Contributions||Eichhorn, Gunther Louis, 1927-, National Institutes of Health (U.S.)|
|The Physical Object|
|Pagination|| p. :|
David Sinclair, PhD, is a professor of genetics and a codirector of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School. His research has advanced our understanding of how we age and how to slow these processes. He is the author of Lifespan and has a website by. Aging is influenced by many intrinsic and extrinsic factors including genetic background, epigenetics, diet, and environment. Our ability to develop a complete model of the aging process and accurately predict outcomes designed to extend lifespan or treat age-associated pathology requires identification of the range of factors capable of influence aging and an understanding of how these.
This paper pinpointed the gene that causes the syndrome. The protein it encodes is 1, amino acids in length and appears to be in the family of proteins known as DNA helicases, which unwind double-stranded DNA, according to Gerard D. Schellenberg, associate director for research, Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center in Seattle. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease.
The Mystery of Aging How genes and environment affect health and longevity. as I argue in my new book, Exercise is Medicine, is, of course, exercise. But other things help determine longer. Read chapter COMMITTEE BIOGRAPHIES: Aging in Today's Environment Below is the uncorrected machine-read text of this chapter, intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text of each book.
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According to the genetic theory of aging, your genes (as well as mutations in those genes) are responsible for how long you'll live.
Here's what you should know about genes and longevity, and where genetics fits in among the various theories of aging.
The purpose of this book is threefold: first, to inform researchers and clinicians in gerontology about the behavioral genetic perspective; second, to present an overview of what is known about genetic and environmental influences on behavioral aging; and, finally, to stimulate future work in this field by discussing what is not yet known but.
Aging, healthy aging, and longevity. The phenotypes used in studies of the genetics of human aging are usually lifespan (age at death), longevity (long Aging, usually defined as being a specific advanced age or older at the time of study), exceptional longevity (defined as attaining or exceeding a specific exceptional age), or healthy aging (a combination of old age and health, often defined as Cited by: Gene-by-environment interaction (G × E) designs can be genetics and the environment book to understand how individual difference characteristics, such as personality, might moderate genetic and environmental influences on successful aging outcomes.
Application of such methods can clarify the interplay of genes, environments, personality, and successful by: This book explores this variability. Following an overview of family, adoption and twin studies of genetic and environmental influences on ageing, the author examines such topics as: longevity and health research; cognitive functioning, personality and psychopathology; and social support, life events and family environment by: Genetics of aging is generally concerned with life extension associated with genetic alterations, rather than with accelerated aging diseases leading to reduction in lifespan.
The first mutation found to increase longevity in an animal was the age-1 gene in Caenorhabditis l Klass discovered that lifespan of C.
elegans could be altered by mutations, but Klass believed that the. SUCCESSFUL AGING is an essential book for the rest of your life.”—Daniel H. Pink, author of When and Drive “Daniel Levitin explores a wealth of information on the complex biology of aging and presents it in an engaging and accessible manner/5(89).
Aging: genetic and environmental influences. Thoughtfully written, Aging presents an overview of what is known about genetic and environmental influences on aging.
Beginning with description\/a> \" The book concludes with a summary of the field of gerontological behavioral genetics. This book will stimulate discussion and future. Probing the genetic and molecular bases of aging and aging-related processes in humans and in animal models, Genetics of Aging is a multidisciplinary section publishing research on age-related changes in gene expression, signaling, cell proliferation, cell death, stress responses, and senescence; the genes implicated in age-related diseases and impairment; and the role of stem cells in aging.
The duration of human life (longevity) is influenced by genetics, the environment, and lifestyle. Environmental improvements beginning in the s extended the average life span dramatically with significant improvements in the availability of food and clean water, better housing and living conditions, reduced exposure to infectious diseases, and access to medical care.
A lmost every process in our body changes, however quickly or slowly, as we age. And it’s not just genes that are affected by aging, but the ways we live our lives: the things we’re exposed to.
Physical Environment: Where you live influences how well you age. And there are risks to aging in place. A home with poor lighting, a tricky-to-navigate floor plan, bathrooms that aren’t senior-friendly and stairs can all increase the risk of falls. And falls are the leading cause of fatal and nonfatal injuries for people over The nematode Caenorhabditis elegans ages and dies in a few weeks, but humans can live for years or more.
Assuming that the ancestor. What is aging. • “To grow old or show signs of growing old” Webster’s New World Dictionary, • “a process of intrinsic, progressive, and generalized physical deterioration that occurs over time beginning at about the age of reproductive maturity” Austad, Handbook of the Biology of Aging, Genetic interventions that accelerate or retard aging in mice are crucial in advancing our knowledge over mammalian aging.
Yet determining if a given intervention affects the aging process is not straightforward since, for instance, many disease-causing mutations may decrease life span without affecting aging.
In this work, we employed the Gompertz model to determine whether several Cited by: The Biology of Aging: An Overview Robert J. Pignolo, M.D., Ph.D. Assistant Professor of Medicine Division of Geriatric Medicine Fellow, Institute on Aging.
Genetic and Environmental Sources of Individual Differences in Views on Aging Anna E. Kornadt Bielefeld University Christian Kandler Bielefeld University and Medical School Berlin Views on aging are central psychosocial variables in the aging process, but knowledge about their determinants is File Size: KB.
Aging Genetics and Aging Sandra Rodríguez-Rodero 1, Juan Luis Fernández-Morera 1, Edelmiro Menéndez-Torre 1, Vincenzo Calvanese 2, Agustín F. Fernández 3 and Mario F. Fraga 2,3*. This chapter is intended to provide only a brief summary of the aspects of modern genetics that are relevant to discriminating between various theories of evolution and theories of aging.
(See a genetics textbook such as the excellent GENES VIII by George Lewin for more on genetics.) Since evolution involves the modification and propagation of. -Describes the impact of the environment and diet in modulating epigenetic processes during aging.
Epigenetics of Aging is the first book in this exponentially expanding field, and will be an indispensable source of information for those with interests in epigenetics and/or aging.Introduction It is widely known that natural aging and genetics can determine our health.
However, inan assessment by the World Health Organisation (WHO) (), estimated that, 24% of the global disease burden and 23% of all deaths were directly attributable to environmental factors.Understanding what is aging is very important for the understanding whether aging is a disease or not; consequently, we will approach the definition of aging from this perspective.